Synthetic Cannabinoids Archives - SmokingBlendReviews.com

I’ll quickly point out I am not a lawyer or legal expert of any kind. The information used to support my argument is based on a personal interpretation of the Federal Law S.3187, evidence was utilized from various first hand source (commentary, opinions by non-experts).

In this post we will be discussing the pro and cons of the legal arguments with regards to whether so-called 4th Generation Synthetic cannabinoids (i.e.: UR-144, 5-fur, 5fakb48, sts-135 ) are in fact legal or not.

UR-144, 5-Fur, 5fakb48, sts-135 are all compounds which research chemists claim are post-ban legal. However, I believe it is dangerous to believe some less then reputable chinese company word for it, considering they don’t even sell that kind of research chemical in there market…

One thing people should seriously consider is that law enforcement agencies continue to try and battle against the ever changing landscape of chemical compounds and chemists which are light years ahead of any legislation. Because they have no legal mechanism for legal arrests, they are progressively getting more and more aggressives in how they deal with manufacturers and distributors who are utilizing loop holes in the law. For example:

Louisiana where UR-144 and 5-Fur were used after the state went ahead before the mentioned federal law passed to ban there own list of compounds. But as the industry began to pump out mass production of these new 4 th generation blends, law enforcement began a brutal crack down across that state.

” Hundreds of individuals were arrested around the state. Operations were shut down. Bank accounts were seized and frozen. Countless man-hours and untold money was spent waging this new war on synthetic drugs. The problem was, most of the people who were arrested, and had their businesses shut down and property seized, weren’t breaking any laws. Chemists and law enforcement seemed to agree – UR-144 and 5FUR-144 were legal.” (source: http://nolacriminallaw.com/)

Law enforcement agencies are bullying people out of the industry by outright illegal arrests! What better way to make someone quit there day job then to throw them in jail, reprimand all there money, post there face all over the media (essentially destroy) someone’s life credibility. Sure you will get your cash back maybe not your product however, your reputation will be forever destroyed since what is online stays online forever thanks for stupid GOOGLE and company who cache everything for eternity.

Continuing on to the discussion concerning UR-144 and similar compounds, while they are not specifically listed on the Federal Ban, what is cause for concern is this aspect. The government went ahead and defined what a cannabimimetic agent must be:

a) be a CB1 receptor agonist (and this must be backed up with binding studies and function assay research)

-AND-

b) belong to one of the listed chemical designation classes.

UR-144 and company essentially have an affinity to bind mostly with CB2 receptor however like all synthetics they bind with a very small percentage with CB1 receptor in the brain. UR-144 and company as compounds only fits into category a to certain extend because they mostly bind with CB2 receptor while targeted research chemicals in the past connected entirely with CB1 receptor. Moreover the government stipulates that a study must be conducted of the particular research chemical to prove its affinity to bind with CB1 receptor and also needs to respect the fact that it needs to belong to the designation classes outlined in the legislature. Because of how new UR-144 and company are its unlikely that there are many labs out there equipped to A) test for that particular compound B) that they have conducted the aforementioned study of that particular compound.

Although the legislation is therefore not all-encompassing, this legislature and example about busts and scare tactic is sure to have a very chilling effect on the cannabinoid market in the US because it would leave distributors of other cannabinoids very open to prosecution under the Federal Analog Act. With a sympathetic jury federal prosecutors could easily and successfully argue that AB-001 is an analogue of JWH-018 for example, therefore illegal.

The way the bill is worded does raise some interesting questions though. If a novel cannabinoid derivative within one of these chemical classes is synthesized for which no experimental data on CB1 binding is available then is it uncontrolled? How reasonable is it to expect the layman to know whether there is evidence of CB1 agonism for any particular compound given that such information is generally only documented in scientific journals that are often subscription services with high costs? How reasonable is it to expect distributors of such chemicals to know these things? And if new evidence becomes available that demonstrates a novel compound to be a CB1 agonist then what is a reasonable period of time that those in possession of the compound could remain unaware? The extent to which such a broad law will be enforced remains to be seen too. It certainly presents a challenge for both law enforcement and the courts, so I guess we’ll have to wait and see how effective it proves to be should it pass.

UR-144 while it does not bind with CB1 receptor exclusively, but mostly with CB2 receptors then nonethless it binds with CB1 receptor then making that particular compound outlawed… as long as the government comes up with there stupid study demonstrating that… but still I think its a very large cause for concern…

WORD of caution be SAFE, we live in weird times… where now the US government has unlimited ability to spy on you and everything you do… online. (see article interesting read: http://rt.com/usa/news/nsa-whistleblower-binney-drake-978/)

Introduction to Synthetic Cannabinoids: The Basics

So you think you’re ready to enter the world of synthetic weed, and get STONED with Mr. Wizard…

Common forms of synthetic cannabinoids available on the ‘retail’ market:

Synthetic cannabinoids, they’ve been around for years and years, but somehow only recently emerged into the ‘retail’ online RC and local head shop market. The most common form of synthetic cannabinoid (in this case “legal smoke”) is a mixture of dried plant matter, sprayed with an unknown amount of an unknown cannabinoid. The most common brand names for these are the obvious K2 Incense, Spice Smoking Blend, Serenity Now, and so on and so on. This stuff if not gotten from a reputible supplier, could be either a) bunk b) reallly overly strong or c) looks like fish food and not too appealing in any of these cases. On the other hand there are very reputible and honest suppliers of these ‘incense’ as well

The other form of synthetic cannabinoid you probably are familar with (or are here to become familar with) is the pure lab grade “research chemical” compounds, such as the JWH and WIN families. These chemicals were designed by various research chemists and big pharma style companies (Pfizer, Sterling Winthrop). These chemicals effects vary widely in potentcy, effects, and duration of action depending on the family of cannabinoid and which particular compound of that family you are dealing with.

Routes of administration:

When it comes to ingestion of synthetic cannabinoids, it’s pretty simple. The K2/Spice “Herbal Incense” can be smoked or vaporized just like regular natrually occuring cannabinoids. The synthetic RC cannabinoids on the other hand, can be smoked out of a regular spoon on a bed of ash (see picture below) or screens w/ ash, rolling papers, celluose rolling papers, or whatever works for you best. There is the thought among researchers that some synthetic cannabinoid compounds are destroyed when exposed to direct flame. In this case, oral vaporization with a oil burner meth pipe or aluminum foil (chasing the j-dragon), I’ve even read accounts of absorbsion via insufflation with some of these compounds, WIN 55 being one of them that will be discussed further later. There are many methods of ingestion that will be discussed in greater detail later in the OP. I even tried plugging JWH-018 one night, but I was wrecked on Jim Beam and OxyContin so I dont know if did even did anything at all, but it was in the name of science

General overview of effects:

Generally, it feels like weed, but missing something. Like mentioned before, it really depends on the compounds, dosages, ratios, ROA, among other things that will account to the potentcy and positive-effects. Some of these compounds are several times (even several hundred times ) stronger than THC, some are CB1 agonists, some are CB2 agonist, some are CB1 and 2 agonists. These chemicals are all very unique and their effects their own, and also dependant on the quality of the synthesis. The main positive feelings (or high) of SCs are pretty much identical to that of their natrual cousins THC and CBD, elevated or uplifted mood, hightened creativity or curiosity, a state of relaxation, increased sense of humor, decreased cognitive ability eg: memory loss or “brain farts” (will be discussed in depth later), increased appitite, and time distortion. While also missing some elements described by JWH users (when compared to THC) such as lack of body high or the lack of extreme laziness/severe couchlock. Again, like with everything else, effects, dosage, and duration of these SCs will be discussed in more detail later in the advanced breakdown of the synthetic cannabinoids, their families and related compounds.

Precautions:

This is only an introductory section to this guide, so the warnings and precautions of using SCs recreationally will only be touched on lightly in this paragraph. *This advice should not be considered ‘medical’ advice in any way, but is collected is from reputable web sites, government sources and studies, scientific reports and research, and what
other little documentation exists on these SC compounds*
Eyeballing synthetic very potent lab-grade chemicals
The risk and signs of overdose
The Fear, and tips for dealing with it.
Common sense, something not used enough in the research chemical underworld.

-> Eyeballing: Rule of thumb is, don’t eyeball doses. No matter how many times this is said, people don’t listen (including myself). If you really want to be serious about researching these compounds, you should obtain the proper measurement equipment, links will be provided below. Other than possibly overdosing, whice I’ve done multiple times also, there is one more consequence of irresponsible use and eyeballing measurements of SCs. Because you can continously raise the dosage beyond the ceiling point of THC, eventually your doses will just grow to heroic amounts in order to feel the slightest ‘relaxation’. I’ve also gathered that this tolerance also transfers also to THC, other cannabinoids, and apparently takes forever to go away. I will have to take a picture of how much I use for example why not eyeball chemicals, and how it causes stupid-high-tolerance, and possible addiction.
-> Addiction Potential: Guess what? Remember all those times you heard “marijuana is not addictive” well forget that. Information surfacing after widespread long term illicit use and abuse of these cannabinoids. Some believe because of the way they directly activate cannabinoid receptors, the receptors can grow more dependant on these drugs. Some users have reported (such as myself) withdrawal phenomenon occuring within 24 hours of ceasing intake of cannabinoids.
-> Overdose: This is something very easy for you to do with these potent cannabinoids, mainly when you are using the pure chemical prepreations. While it is thought that these overdoses are nothing more than ‘getting really high’ and are not hamful or fatal, as is with THC, but there is not enough evidence to support any theorys yet. Signs/symptoms of a SC OD are: anxiety or panic attacks, racing heartbeat, racing or looping thoughts (usually negative in subject matter), trouble or shortness of breath, and even reports of audial or visual hallucinations.
-> “The Fear”: You might’ve heard this term thrown around in the old thread, or used to describe an overdose of JWH. The key is, it’s not real, it’s only being caused by an over excitement of your cannabinoid receptors. Try to listen to some upbeat music, read, watch tv, or something to get your mind off the panic. If those options fail, you can try taking a shower, eating a lot of food, or going for a brisk run.
-> Common sense: Remember, this stuff is strong, potent by weight, cheap, and easily available to most worldwide. Common sense MUST be practiced with these drugs even more so than more-so “run of the mill” street recreational drugs. Don’t give your friend who only smokes a little weed at parties a dime baggie with 50mg of JWH-018 powder in it, and tell him to dig in. You know, common sense like that.

Drug Testing

Until recently, these SCs weren’t detectable in any drug tests on the market anywhere. Now there are a labs that currently offer LC/MS/MS (thats right, double MS) urinalyasis detection of JWH-018 and JWH-073 two SCs identified in “27 herbal smoking mixtures”, and well as supposedly “establishedtest methods to identify the presence of their metabolites”. There is also currently labs offering blood tests that can confirm JWH-018, 019, 073, and 250. Well this sucks, thank god for researchers that have jobs, probation officers, or otherwise faggots that interfere with their research, these are only detectable in urine for up to 72 hours. Finally at least there is some part-science probably part propaganda ‘official’ look into drug testing for JWHes here

Legality

The US Drug Enforcement Administration have announced that they are using the emergency scheduling law to ban 5 common synthetic cannabinoid compounds (including JWH-018, JWH-073, and JWH-200). Obviously there are hundreds more compounds available and that are pretty much (just would like to stress: pretty much) completely legal around the world, with the exception of a few cutting-edge countries of the world, and an increasing number of US States and even local/county governments are beginning the slow crackdown on these “legal THC alternatives” The Drug Enforcement Agency identified the “Spice Cannabinoids” as a drug or chemical of concern in 2009. Please if I am missing any Countries, US states, or US municipalities (entire list coming soon) that you know the current legal status, feel free to reply and let us know about the legal status in your hometown!

Countries to ban one or more SC
Austria, Belarus, Canada, France, Germany, Ireland, Italy, Latvia, Poland, South Korea (but not North?), Sweden, Estonia, Romania, Russia, Ukraine, United States and the United Kingdom

Are 4th Generation Synthetic cannabinoids Legal or Not?

Basics of SC Spice Blends